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KMID : 0386119920280030435
Journal of the Korean Radiological Society
1992 Volume.28 No. 3 p.435 ~ p.440
Transphyseal Extension of Osteosarcoma: MRI and Pathologic Correlation
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Abstract
We retrospectively analysed plain radiographs and MR imaging of 16 conventional osteosarcoma cases(8 children, 8 adults) which underwent amputations or limb salvage operations. Pathologic correlation was performed with gross and microscopic
sections to
evaluate 1) whether the open epiphyseal plate can function as a barrier against transphyseal spread of osteosarcoma and 2) the diagnostic value of MR imaging for the detection of the detection of the epiphyseal involvement of osteosarcoma. In
children
with open epiphyseal plates, conventional radiographs suggested transphyseal tumor growth in one of eight cases(12.5%0 and MR imaging in seven cases(87.5%). Pathologic examination confirmed epiphyseal involvement in six of seven cases noted with
MR
imaging(75%). On the the other hand, in adult patients with closed epiphyseal plates, conventional radiographs showed transphyseal tumor growth in six of eight cases(75%), while MR imaging and pathologic exam demonstrated tumor invasion in all
cases(100%).
We conclude that open epiphyseal plate does not function as and effective barrier against tumor extension, and MR imaging is an excellent method in detecting the extent of transphyseal tumor growth.
KEYWORD
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